改善腸漏
羅伊氏乳酸桿菌DSM 17938可通過缩緊上皮細胞間的緊密連結, 增加上皮細胞生長, 快速更換受損上皮細胞, 降低腸道滲透性, 強化黏膜的屏障功能來改善腸漏症。
羅伊氏乳酸桿菌缩緊上皮細胞間的緊密連結 (１)
- 乳酸 (Lactic acid): 乳酸可降低腸道的pH值, 有利提供了乳酸桿菌 (lactobailli) 和雙歧桿菌 (bifidobacteria) 更好的生長的環境。
- 乙酸 (Acetic acid): 乙酸除了具有降低pH值的作用外, 還對許多病原體具有抗菌作用。
- 羅伊氏素 (Reuterin): 羅伊氏乳酸桿菌DSM 17938將甘油轉化為羅伊氏素, 從而引起氧化應激並抑制病原體（細菌, 病毒, 真菌）的生長
羅伊氏乳酸桿菌缩緊上皮細胞間的緊密連結, 減少細菌滲透, 細胞發炎(2,3)
羅伊氏乳酸桿菌DSM 17938促進上皮細胞生長, 遷移和清除(4)
羅伊氏乳酸桿菌DSM 17938縮短腹瀉天數以及嚴重程度(5)
羅伊氏乳酸桿菌DSM17938改善健康
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參考
- Ivan A. Casas & Walter J. Dobrogosz (2000) Validation of the Probiotic Concept: Lactobacillus reuteri Confers Broad-spectrum Protection against Disease in Humans and Animals, Microbial Ecology in Health and Disease, 12:4, 247-285, DOI: 10.1080/08910600050216246-1
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- Dicksved J, Schreiber O, Willing B, Petersson J, Rang S, Phillipson M, Holm L, Roos S. Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction. PLoS One. 2012;7(9):e46399. doi: 10.1371/journal.pone.0046399. Epub 2012 Sep 27. PMID: 23029509; PMCID: PMC3459901.
- Preidis GA, Saulnier DM, Blutt SE, Mistretta TA, Riehle KP, Major AM, Venable SF, Finegold MJ, Petrosino JF, Conner ME, Versalovic J. Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine. FASEB J. 2012 May;26(5):1960-9. doi: 10.1096/fj.10-177980. Epub 2012 Jan 20. PMID: 22267340; PMCID: PMC3336785.
- Shornikova AV, Casas IA, Isolauri E, Mykkänen H, Vesikari T. Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children. J Pediatr Gastroenterol Nutr. 1997 Apr;24(4):399-404. doi: 10.1097/00005176-199704000-00008. PMID: 9144122.